Ziritaxestat Drug-Drug Interaction with Oral Contraceptives: Role of SULT1E1 Inhibition - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35713964/
In vitro signals indicate that ziritaxestat is a weak cytochrome P450 (CYP) 3A4 inhibitor and inducer. Therefore, potential drug-drug interactions (DDIs) with oral contraceptives were examined at a time when...
Relevance: In vitro signals indicate that ziritaxestat is a weak cytochrome P450 (CYP) 3A4 inhibitor and inducer. Therefore, potential drug-drug interactions (DDIs) with oral contraceptives were examined at a time when ziritaxestat was under development for treatment of fibrotic diseases.
Fulfillment of Desired Postpartum Permanent Contraception: a Health Disparities Issue - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35713848/
Women of color experience marked disparities in fulfillment of desired postpartum permanent contraception. While many attribute the disparity to the required Medicaid sterilization consent form and 30-day waiting period established...
Relevance: Women of color experience marked disparities in fulfillment of desired postpartum permanent contraception. While many attribute the disparity to the required Medicaid sterilization consent form and 30-day waiting period established in response to forced and coerced sterilizations, the policy does not entirely explain the disparity;...
Uptake of long-acting reversible contraception after telemedicine delivered abortion during Covid-19
Source : https://www.tandfonline.com/doi/abs/10.1080/13625187.2022.2085680?journalCode=iejc20
Abstract During COVID-19, early medical abortion (EMA) at home in Scotland was largely delivered by telemedicine. Short-acting post-abortion contraception was provided with EMA medications, but long-acting reversible contraception (LARC) (implant,...
Conclusion: During COVID-19 there was demand for post-abortion LARC but less than half of patients received this by six weeks. Provision was enhanced when in-person clinical interactions took place. Interventions are required to facilitate timely access and initiation of LARC with telemedicine delivered abortion care.
Delayed pregnancy detection and return to fertility with extended levonorgestrel-containing oral contraceptives: A real world setting cohort study - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35713281/
Small differences were observed for pregnancy rates and delayed pregnancy detection between 91-day extended COC LNG and 28-day COC LNG , which may be related to the longer days' supply...
Conclusions: Small differences were observed for pregnancy rates and delayed pregnancy detection between 91-day extended COCLNG and 28-day COCLNG, which may be related to the longer days’ supply of extended COCLNG. Differences in the fertility analysis may be related to unmeasured residual confounding.
A reconfigurable microfluidic building block platform for high-throughput nonhormonal contraceptive screening - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35678283/
doi: 10.1039/d2lc00424k. Online ahead of print. 1 Department of Biomedical Engineering, The Pennsylvania State University, University Park, PA, 16802, USA. [email protected]. 2 Department of Animal Science, The Pennsylvania State University,...
Relevance: Identifying nonhormonal contraceptives will have profound impacts on avoiding side effects of hormonal birth control methods, minimizing pregnancy complications and infant mortality rates, and promoting family planning.