Discussion: A 45-year-old female presented with a mass sensation per abdomen for the last five months. An abdominal ultrasound revealed multiple uterine fibroids. Contrast-enhanced magnetic resonance imaging revealed a large multiloculated abdominopelvic mass arising from the fundus of the uterus, along with multiple smaller subserosal fibroids.

Discussion: The relevance of performing extemporaneous biopsy to discard malignancy characteristic of the tissue with subsequent histology confirmation, especially in those cases like this one where high vascularity was observed before surgery and visible differences like thicknesses with irregular borders were seen.

Conclusion: Compared with HIFU alone, the therapeutic efficacy of the heterogeneous hyperintense fibroids may be enhanced by GnRH-a pretreated with HIFU, however it is important to rule out the slightly homogeneous hyperintense fibroids.

Conclusion: In managing a patient with early pregnancy and a history of fibroids presenting with sciatic pain, one should consider conservative management such as analgesic control and close monitoring after ruling out other probable causes.

Conclusion: The total fibroid volume declined on average throughout pregnancy. However, summarizing across all fibroids disguises substantial heterogeneity by starting total fibroid volume and maternal characteristics.