Association of uterine fibroids with birthweight and gestational age - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/32741603/
doi: 10.1016/j.annepidem.2020.06.012. 1 Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN. 2 Department of Medicine, Vanderbilt University Medical Center, Nashville, TN. 3 Vanderbilt Epidemiology Center, Vanderbilt University Medical Center,...
Discussion: Race or ethnicity substantially confounds the associations. The clinical belief that uterine fibroids impair fetal growth is supported only by a significant decrease in birthweight for women with multiple fibroids. Updated 7/22.
TODAY: Misdiagnosed as Cancer, Woman Has Watermelon-Sized Uterine Fibroid Removed
TODAY: Misdiagnosed as Cancer, Woman Has Watermelon-Sized Uterine Fibroid Removed N atalie Suflita, a 35-year-old from Rochester, New York, noticed lower back pressure and numbness in her legs when she...
Discussion: “The mass took up basically her entire abdomen. But I could tell that it had a lot of the key characteristics of a fibroid on her imaging,” says Dr. Shirazian. “It was attached to the uterus, but could be separated while still maintaining her fertility.”
Association of uterine fibroids with birthweight and gestational age.
Source : https://www.vumc.org/whr/publication/association-uterine-fibroids-birthweight-and-gestational-age
Association of uterine fibroids with birthweight and gestational age. Annals of epidemiology. 2020 Dec;50(50). 35-40.e2.32741603 [PubMed]
Discussion: Endometrial hyperplasia is the result of chronic exposure to estrogen along with a relative deficiency of progesterone.
Treatment for uterine fibroids
Source : https://www.fhi.no/en/publ/2022/Treatment-for-uterine-fibroids/
Uterine fibroids are made of a type of muscle cells and connective tissue that grow on the wall of the uterus. About eight out of ten women have uterine fibroids,...
Discussion: We found one randomized study and a health technology assessment on the effect of combination therapy with gonadotrophin-releasing hormone receptor antagonist and two Cochrane reviews on non-steroidal anti-inflammatory drugs and progestogen, respectively.
Myometrial oxidative stress drives MED12 mutations in leiomyoma - Cell & Bioscience
Source : https://cellandbioscience.biomedcentral.com/articles/10.1186/s13578-022-00852-0
Background More than 70% of leiomyomas (LM) harbor MED12 mutations, primarily in exon 2 at c.130-131(GG). The cause of MED12 mutations in myometrial cells remains largely unknown. We hypothesized that...
Conclusion: Together, our data identified a clear connection between increased myometrial oxidative stress and a high rate of MED12 mutations that may underlie the risk of LM development and severity in women of reproductive age.