Prolonged Cadmium Exposure Alters Migration Dynamics and Increases Heterogeneity of Human Uterine Fibroid Cells-Insights from Time Lapse Analysis
Source : https://www.mdpi.com/2227-9059/10/4/917
Cadmium (Cd) is one of the most prevalent environmental heavy metal contaminants and is considered an endocrine disruptor and carcinogen. In women with uterine fibroids, there is a correlation between...
Conclusion/Relevance: Cadmium (Cd) is one of the most prevalent environmental heavy metal contaminants and is considered an endocrine disruptor and carcinogen. In women with uterine fibroids, there is a correlation between blood Cd levels and fibroid tumor size. In this study, fibroid cells were exposed to 10 µM CdCl2 for 6 months and a...
'I thought I had fibroids, and now I don't': a mixed method study on health-related quality of life in uterine sarcoma patients - Health and Quality of Life Outcomes
Source : https://hqlo.biomedcentral.com/articles/10.1186/s12955-022-01971-5
Background Uterine sarcomas are rare subtypes of primary urogenital tumours and need tailored treatment. This study aimed to examine the impact of diagnosis and treatment on health-related quality of life...
Conclusions: Uterine sarcoma patients experience a variety of concerns covering the physical, mental, and social domains of HRQoL that are in the main EORTC instruments, but not all of them. Combining cancer-generic, location- and sarcoma-specific items is recommended to assess HRQoL in this patient group.
Analysis of Clinical Efficacy of Laparoendoscopic Single-Site Surgery for Uterine Fibroids
Source : https://www.hindawi.com/journals/jhe/2022/5606998/
In order to determine the clinical efficacy of laparoendoscopic single-site surgery (LESS) for uterine fibroids (UFs), the study population comprises 65 patients who underwent hysteromyoma enucleation in our hospital from...
Conclusion/Relevance: To sum up, LESS-M is more advantageous over MLS-M for the treatment of UFs and deserves to be popularized and applied clinically because it causes less physical damage to patients, with the ability to promote patients' postoperative recovery, reduce postoperative pain, and improve QOL and surgical satisfaction.
Preoperative Differentiation of Uterine Leiomyomas and Leiomyosarcomas: Current Possibilities and Future Directions
Source : https://www.mdpi.com/2072-6694/14/8/1966
The distinguishing of uterine leiomyosarcomas (ULMS) and uterine leiomyomas (ULM) before the operation and histopathological evaluation of tissue is one of the current challenges for clinicians and researchers. Recently, a...
Conclusion/Relevance: In our review, we focus on the possible methods to diagnose uterine lesions effectively, including clinical signs and symptoms, laboratory tests, imaging methods, molecular aspects, available scales, and AI. In addition, considering costs and availability, we list the most promising methods to be implemented and...
Uterine fibroids increase the risk of thyroid goiter and thyroid nodules - Scientific Reports
Source : https://www.nature.com/articles/s41598-022-10625-x
Uterine fibroid and benign thyroid disease are both common diseases in women. This study aimed to evaluate whether these diseases are related. We established the uterine fibroid group according to...
Conclusion: Although the mechanism is not well known, estrogen and iodide might be a link between uterine fibroids and thyroid goiters and nodules. Future studies that prospectively follow women with uterine fibroids across a lifetime are needed.